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Pharmaceutical Intermediates

1-Methyl-1H-Indazole-3-Carboxylic Acid

Core heterocyclic indazole acid coupled to granatane amine to manufacture Granisetron antiemetic.

1-Methyl-1H-Indazole-3-Carboxylic Acid
CAS Number
50890-83-0
Molecular Formula
C9H8N2O2
Molecular Weight
176.17 g/mol
Therapeutic Category
Granisetron HCl Intermediate
Purity
≥ 99.0%
Grade
IP / BP / USP / EP
Appearance
Off-white to light tan crystalline powder
Solubility
Soluble in DMSO and DMF; sparingly soluble in Methanol
Storage
Store below 25 °C in a tightly closed container, protected from light and moisture
Packaging
25 kg HDPE drum with double LDPE inner liner
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Product Overview

Core heterocyclic indazole acid coupled to granatane amine to manufacture Granisetron antiemetic.

Manufactured at Harvinlabs WHO-GMP certified facility in Panoli, Ankleshwar under strict quality control standards. Supplied with batch-specific Certificate of Analysis (CoA), HPLC/GC purity reports, and full regulatory documentation.

Applications

  • Granisetron Hydrochloride API
  • 5-HT3 Receptor Antagonist Synthesis
  • Indazole Heterocycles

Specifications

Parameter Specification
Appearance Off-white to light tan crystalline powder
Identification Complies by IR and HPLC/GC
Purity (Assay) ≥ 99.0%
Single Impurity NMT 0.10%
Loss on Drying NMT 0.5%
Residue on Ignition NMT 0.1%
Heavy Metals NMT 10 ppm

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Our regulatory team supplies DMF, COA, MSDS and stability data on request.

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1-Methyl-1H-Indazole-3-Carboxylic Acid

CAS 50890-83-0