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Pharmaceutical Intermediates

10,11-Dihydro-11-oxodibenzo[b,f][1,4]thiazepine (DBTO)

Tricyclic thiazepine intermediate serving as the core skeleton of Quetiapine Fumarate antipsychotic API.

10,11-Dihydro-11-oxodibenzo[b,f][1,4]thiazepine (DBTO)
CAS Number
3159-07-7
Molecular Formula
C13H9NOS
Molecular Weight
227.28 g/mol
Therapeutic Category
Quetiapine Intermediate
Purity
≥ 99.0%
Grade
IP / BP / USP / EP
Appearance
Off-white to pale yellow crystalline powder
Solubility
Soluble in DMF and DMSO; slightly soluble in Ethanol
Storage
Store below 25 °C in a tightly closed container, protected from light and moisture
Packaging
25 kg HDPE drum with double LDPE inner liner
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Product Overview

Tricyclic thiazepine intermediate serving as the core skeleton of Quetiapine Fumarate antipsychotic API.

Manufactured at Harvinlabs WHO-GMP certified facility in Panoli, Ankleshwar under strict quality control standards. Supplied with batch-specific Certificate of Analysis (CoA), HPLC/GC purity reports, and full regulatory documentation.

Applications

  • Quetiapine Fumarate API Synthesis
  • Antipsychotic Drug Intermediates
  • Thiazepine Chemistry

Specifications

Parameter Specification
Appearance Off-white to pale yellow crystalline powder
Identification Complies by IR and HPLC/GC
Purity (Assay) ≥ 99.0%
Single Impurity NMT 0.10%
Loss on Drying NMT 0.5%
Residue on Ignition NMT 0.1%
Heavy Metals NMT 10 ppm

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Our regulatory team supplies DMF, COA, MSDS and stability data on request.

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10,11-Dihydro-11-oxodibenzo[b,f][1,4]thiazepine (DBTO)

CAS 3159-07-7